What is Nerium EHT

What is Nerium EHT?

Does an All-Natural Age Defying and Regenerating Supplement Interest You?

Genetics, the Environment, and Stress Kills – Nerium EHT May Be Your Protective Mechanism

Nerium International is the company that proudly holds exclusive rights to this preventative, restorative, and regenerating natural compound that may help you age better, think clearer, improve brain function, and prevent and recover faster and more effectively from head trauma.

Sounds like a miracle – Many researchers believe it is!

Scientific researchers know time kills the brain. Vital neuron connections weaken and break, triggering memory loss and slower reaction time and alertness. Recent studies have shown EHT is a new compilation age-defying supplement that effectively helps prevent mental decline with a new mixture centered around EHT extract, which is a natural formula of bioactive molecules derived from coffee. This incredible formula is combined with a diverse range of essential vitamins, including B6, B12, D3, folic acid, magnesium citrate, selenium, Huperine A (boosts focus), and the protective antioxidant lipoic acid, to trigger…

  • Better overall brain health and communication
  • Defense against oxidative stress and chronic swelling and inflammation
  • Enhances and certifies improved natural brain function
  • Supports and protects intricate neuron pathways in your brain
  • Boosts natural energy stores
  • Improves attention and focus

Where Does EHT Come From?

Dr. Jeffry Stock and his team discovered the EHT molecule after 20 years of research and testing. It was founded in the infamous neuroscience lab in Princeton University. This science-based powerful molecule supports strengthened neuron connection, which leads to regeneration and more resilient synaptic connections within the brain.

Bottom Line…Enhanced brain function and performance for a focused, healthy, and more resilient mind long-term.

Let’s look briefly at the bioscience of EHT – the changing of the brain.

Without your brain you wouldn’t be able to move or control your senses, feelings, and thought process. A lifetime of memories are stored within your brain and unfortunately time takes its toll and interferes with the retrieval process. It just gets weaker naturally as the clock ticks.

Aging weakens the neuron structures within your brain and from this neurodegenerative diseases form. Your brain cells inevitably start dying and forgetfulness, shaking, mood changes, and decreased motor function result. There are all sorts of triggers or causes but the “big picture” culprit stems from how healthy your brain is.

I’m sure you’ve noticed this in yourself or older people. As we age we experience less motility and mobility, we start forgetting things, and health issues become more of a focal point. Researchers are looking to find connectors that help improve brain health and promote stronger and more resilient brain function, along with faster and more thorough repair when the brain is injured. Think of it like a fountain of youth for the brain.

EHT Discovered!

EHT is an extract consisting naturally of a calculated mix of bioactive molecules. What researchers have found is that by using this compound regularly you can help protect and strengthen the neuron function of the brain. This helps to prevent injury and maintain optimal function. And when combined with a healthy diet, regular exercise, and a positive lifestyle you can actually slow or perhaps even stop the once thought inevitable pace in which the brain ages, with leads to eventual total breakdown and death.

This groundbreaking discovery now raises the question as to what degree this formula can prevent head injury in sport and safely speed up the recovery time. Exciting and alive EHT shows much promise for the future of healthy brain function. A natural product that might well become a routine useful prevention tool for many in sports, the aging process, and life in general!

 

 

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Buy Nerium EHT for a Limited Time Only

The wait is over! Nerium EHT is now available to buy but only for a limited time. Chances are Nerium will sell out very quickly and if you want to get your hands on some before it goes on general release in August then you better order quickly.

Nerium Released EHT today (May 15th 2015) and as of now (8am) the servers are offline due to the amount of web volume. We are frantically trying to order on this end in hopes of getting our hands on Nerium EHT.

Buy Nerium EHT Brain Supplement

 

Click Here to Buy Nerium EHT,
As This WILL Sell Out Fast

Click Here to Purchase Nerium EHT

 

Benefits of Nerium EHT supplement

Benefits of Nerium EHT

Here are a few of the benefits of Nerium EHT

  • Improves Memory Recall
  • Increases Focus and Mental Alertness
  • Protects and Supports Neuronal Networking
  • Promotes Better Cognitive Function
  • Promotes Overall Brain Health
  • Boosts the Body’s Immune System
  • Fortifies and Strengthens Natural Brain Functions
  • Enhances the Body’s Natural Energy Stores

Benefits of nerium eht age defying supplement

For a more detailed view of review of Nerium EHT or to read the published white papers on Nerium EHT visit Supporting Published Evidence for Nerium EHT, PP2A and its Ingredients.

Click Here to Purchase Nerium EHT

Supporting Published Evidence for Nerium EHT, PP2A and its Ingredients.

Nerium EHT was developed at Signum Biosciences in collaboration with Princeton University (Department of Molecular Biology). Research was funded in part by the National Institute of Health, the Michael J. Fox Foundation, and the Alzheimer’s Drug Discovery Foundation.

Nerium EHT – A Breakthrough Discovery

Only NeriumEHT contains EHT™ (Eicosanoyl-5-hydroxytryptamide). Our one-of-a-kind proprietary ingredient is a naturally occurring mix of bioactive molecules isolated from coffee that helps to fortify, protect and enhance your mind. EHT™ modulates PP2A, a key master regulator protein and improves performance, including restoration of cognitive and motor deficits in animal models of neurodegeneration.

How does EHT™ Protect?

  • Helps protect neuronal structural integrity to allow robust signaling by modulating PP2A
  • Reduces damage caused by inflammation
  • Guards against oxidative stress

How does EHT™ Enhance?

  • Optimizes PP2A activity
  • Increases cognitive function and provides neuroprotection
  • Enhances memory circuit connections and slows neurodegeneration

Additional Support

Chronic inflammation is an unfortunate condition caused by a number of factors including brain injury (CTE), aging, toxins (smoking/drinking), and stroke. Chronic inflammation can cause significant neuronal damage in the brain with an excessive release of cytokines and inflammatory mediators causing additional damage. NeriumEHT protects your neurons and promotes brain health by reducing inflammation and pro-inflammatory cytokines.

The Following Studies Demonstrate EHT Provides Cognitive Support.

  1. Therapeutic benefits of a component of coffee in a rat model of Alzheimer’s disease. Basurto-Islas G, Blanchard J, Tung YC, Fernandez JR, Voronkov M, Stock M, Zhang S, Stock JB, Iqbal, K. Neurobiol Aging. 2014. (Epub ahead of print). PMID: 25034344
  2. Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson’s Disease. Lee KW, Im JY, Woo JM, Grosso H, Kim YS, Cristovao AC, Sonsalla PK, Schuster DS, Jalbut MM, Fernandez JR, Voronkov M, Junn E, Braithwaite SP, Stock JB, Mouradian MM. Neurotherapeutics. 2013. 10(1):143-53. PMID: 23296837
  3. Enhanced phosphatase activity attenuates a-synucleinopathy in a mouse model. Lee KW, Chen W, Junn E, Im JY, Grosso H, Sonsalla PK, Feng X, Ray N, Fernandez JR, Chao Y, Masliah E, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. J Neurosci. 2011. 11:31(19):6963-71. PMID: 21562258

The Following Studies Demonstrates That One or More of the Components of Nerium EHT Provides Cognitive Support and/or Protection.

  1. Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial. De Jager CA, Oulhaj A, Jacoby R, Refsum H, Smith AD. Int J Geriatr Psychiatry. 2012. 27(6):592-600 PMID: 21780182
  2. Oral folic acid and vitamin B12 supplementation to prevent cognitive decline in community dwelling older adults with depressive symptoms – the Beyond Ageing Project: a randomized controlled trial. Walker JG, Batterham PJ, Mackinnon AJ, Jorm, AF, Hickie I, Fenech M, Kljakovic M, Crisp D, Christensen H. Am J Clin Nutr. 2012. Jan; 95(1):194-203. PMID: 22170358
  3. Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial.Smith AD, Smith SM, de Jager CA, Whitbread P, Johnston C, Agacinski G, Oulhaj A, Bradley KM, Jacoby R, Refsum H. PLoS One. 2010. 5(9):e12244.PMID: 20838622
  4. A randomized double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer’s disease. Connelly PJ, Prentice NP, Cousland G, Bonham J. Int J Geriatr Psychiatry. 2008. 23(2):155-60. PMID: 17600848
  5. Enhancement of learning and memory by elevating brain magnesium. Slutsky I, Abumaria N, Wu LJ, Huang C, Zhang L, Zhao X, Govindarajan A, Zhao MG, Zhuo M, Tonegawa S, Liu G. Neuron 2010. 65(2):165-177. PMID: 20152124

 The Structural Integrity of Your Brain

An essential component to keeping your brain young is the condition of its structural integrity. Neurons are the building blocks of the nervous system and it’s vital to keep the connections robust, between all the neurons in your brain. A major protein that is responsible for maintaining these connections is known as PP2A (Protein phosphatase 2A).

PP2A and Tau

Your brain is made up of a network of cells known as neurons. Neurons are all connected by axons, the structure of which is maintained by tau proteins binding to microtubules that run along the length of the axon. The PP2A system is a process that binds to tau, ensuring the microtubules stay strong, maintains robust connections and thus healthy neurons.

Between aging, poor diet, lack of exercise and concussive damage, PP2A activity is compromised, leading to hyperphosphorylation of tau. In other words, the binding process of tau to the microtubules is compromised causing them to weaken and separate. When this happens, the neurons are destabilized making them unhealthy.

PP2A and Alpha-synuclein

Alpha-synuclein is another protein which lives at the tip of each neuron in a structure known as the presynaptic terminal, an essential part of how neurons communicate with one another.
Similar to tau, alpha-synuclein is programmed by the same master protein regulator— PP2A. Just like tau, when PP2A activity is compromised, it can cause the hyperphosphorylation of alpha-synuclein which may lead to irreversible damage and neurodegenerative disease.

So now that you understand how essential the PP2A system is to overall brain health and function, what can you do about it?

EHT™, the proprietary ingredient in NeriumEHT, is a naturally occurring botanically derived mix of bioactive molecules that helps to regulate the PP2A system. Therefore, it assists in the stabilization of brain integrity, restores motor function, promotes balanced brain chemistry and improves overall brain health.

The following studies demonstrate PP2A is an important regulator in neurodegeneration and cognition

  1. Protein phosphatase 2A dysfunction in Alzheimer’s disease. Sontag JM, Sontag E. Front Mol Neurosci. 2014. 11;7:16. PMID: 24653673
  2. How it all started: tau and protein phosphatase 2A. Liu C., Gotz J. J Alzheimer’s Dis. 2013. 37(3):483-494. PMID: 23948891
  3. Alpha-Synuclein phosphorylation as a therapeutic target in Parkinson’s disease. Braithwaite SP, Stock JB, Mouradian M. Rev Neurosci. 2012. 23(2):191-198. PMID: 22499677
  4. Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3ß. Martin L, Page G, Terro F. Neurochem Int. 2011. 59(2):235-250. PMID: 21672577
  5. Role of PP2A in Alzheimer’s disease. Rudrabhatla P, Pant HC. Curr Alzheimer Res. 2011. 8(6):623-632. PMID: 21605044
  6. PP2A: a novel druggable target for Alzheimer’s disease. Voronkov M, Braithwaite SP, Stock JB. Future Med Chem. 2011. 3(7):821-833. PMID: 21644827
  7. B vitamin deficiency promotes tau phosphorylation through regulation of GSK3ß and PP2A. Nicolia V, Fuso A, Cavallaro RA, Di Luzio A, Scarpa S. J Alzheimers Dis. 2010. 19(3):895-907. PMID: 20157245
  8. The carboxy-terminal fragment of inhibitor-2 of PP2A induces Alzheimer disease pathology and cognitive impairment. Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden RM, Radu A, Grundke-Iqbal I, Iqbal K. FASEB J. 2010. 24(11):4420-4432. PMID: 20651003
  9. Inhibition of GSK3ß downregulates total tau proteins in cultured neurons and its reversal by the blockade of PP2A. Martin L, Magnaudeix A, Esclaire F, Yardin C, Terro F. J Brain Res. 2009. 3(1252):66-75. PMID: 19071093
  10. Structural mechanism of demethylation and inactivation of PP2A. Xing Y, Li Z, Chen Y, Stock JB, Jeffrey PD, Shi Y. Cell. 2008. 133:154-63. PMID: 18394995
  11. PP2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation. Sontag E, Craig VN, Sontag JM, Arrastia RD, Ogris E, Dayal S, Lentz SR, Arning E, Bottiglieri T. Journal of Neuroscience. 2007. 27(11):2751-2759 PMID: 17360897
  12. Downregulation of PP2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. Sontag E, Hladik C, Montgomery L, Luangpirom A, Mudrak I, Ogris E, White C. Journal of Neuropath & Exp Neurology. 2004. 62(10):1080-1091 PMID: 15535135
  13. PP2A methylation: a link between elevated plasma homocysteine and Alzheimer’s Disease. Vafai S, Stock JB. FEBS Lett. 2002. 518, 1-4. PMID: 11997007

NFL Players Sydney Rice and Steve Weatherford Donate their Brains to Science

Neriums New EHT Mind Enhancement Supplement has been at the center of the media lately as the discussion on the importance of brain health advances. Not only is it an innovative, patented ingredient that comes from EHT comes from 20 years of research out of Dr. Jeffry Stock’s Princeton University labs, but it also has the backing of some major NFL players that have donated their brains to medicl science.

Catch up on the latest interviews with the 2 NFL stars

 

Click Here to Purchase Nerium EHT

Buy Nerium EHT Brain Supplement On Sale May 15

Nerium’s Brain Enhancement Supplement Begins Friday May 15th

Nerium’s highly anticipated EHT ® Age-Defying Supplement, Mind Enhancement Formula goes on pre-sale on Friday, May 15 in the United States.

This Age-Defying Supplement works to protect the brain against mental decline and decreased function associated with aging.

The EHT patented extract, a natural mixture of bioactive molecules isolated from coffee, functions by helping strengthen the brain by maintaining robust and healthy neuron connections.

Along with other key ingredients such as B6, B12, D3, Folic Acid, Selenium, and Liopic Acid, this supplement helps create:

  • Stronger cognitive function and overall brain health
  • Fortification of natural brain functions
  • Protection of neuronal networking
  • Enhancement of the body’s natural energy stores
  • A boost to the body’s immune system
  • Increased focus

Pre-Sale for EHT will be available while supplies last. They will be sold in packages of (3). Each package provides a 30-day supply.

What will pricing be?

The (3) EHT packages will cost:

  • Retail: $210 USD
  • Wholesale: $180 USD
  • Auto-Delivery Order Customer/Brand Partner Pricing: $150 USD

Click here to learn about becoming a Brand Partner

EHT will not be available as an ADO item until August 1.

What will the purchase limit be?
There will be a limit of (3) 3-Packs per transaction.

Who can purchase Nerium EHT?
EHT can be purchased by retail and preferred customers, as well as brand partners in the United States.

Where do you purchase Nerium EHT?
Preferred Customers and Brand Partners will purchase EHT during the pre-sale in their Online Business Center.

Anyone can make a retail purchase of EHT by visiting www.Nerium.com.

Click Here to Purchase Nerium EHT

Where can I watch Videos about Nerium EHT?

Check out the two Nerium EHT videos below

 

 

Also for those that need more in-depth scientific information on EHT, you can share these papers from Signum Biosciences;

EHT- Fighting the Aging Process Physically and Mentally
EHT- The Changing Brain
EHT-Brain Power

We are very excited for you to experience this breakthrough product!

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Nerium EHT Age Defying Supplement-for Brain Health

Nerium EHT Age-Defying Supplement!

Breaking News! Nerium International obtains exclusive global rights to patented EHT® molecule. Nerium EHT Pre-Release Sale starts on May 15, 2015

Nerium EHT Age Defying Supplement for Optimal Brain Health

What is EHT®?

Nerium is dedicated to a comprehensive approach to anti-aging, using exclusive breakthrough ingredients. We are taking our anti-aging product line to the next level with the addition of EHT® , an Age-Defying Supplement that helps protect the brain against mental decline and decreased function that comes with aging. This exclusive patented bio-extract comes after 20 years of research out of Jeffry Stock’s Princeton University labs. EHT creates stronger neural connections, which lead to the ability to create stronger synaptic connections. The result – increased brain performance for a healthy, focused mind.

The Nerium EHT supplement

Nerium EHT Promotes better cognitive function and overall brain health.

  • Fortifies and strengthens natural brain functions.
  • Protects and supports neuronal networking.
  • Enhances the body’s natural energy stores.
  • Boosts the body’s immune system.

Now your face, body, and mind can reflect your youth with Nerium’s product line!

Learn more about the science behind EHT and how it can benefit you.

EHT® in the News

EHT has recently been at the center of media buzz during March’s Brain Injury Awareness month, as it was a leader in advancing the discussion on optimal brain health.

Watch this highlight reel including Fox & Friends, CNN, and more!

Learn More!

Initially this product will be available in the US, with international availability soon! We will have a first-come, first-serve pre-release sale starting May 15. Be one of the first to try this breakthrough product! We will fully introduce EHT into the product lineup on August 1. For more details click here.